ABSTRACT
To explore influence of interventional closure on heart rate in patients with atrial septal defect . Methods : A total of 63 patients with atrial septal defect undergoing percutaneous interventional closure in our hospi‐tal were selected. Heart rate was compared before and after surgery ,and correlation among heart rate ,age ,occlude size and preoperative pulmonary artery pressure was analyzed .Results : Compared with before surgery ,there was significant reduction in heart rate [(75.22 ± 8.23) beats／min vs. (64.87 ± 10. 65) beats／min] after percutaneous in‐terventional closure of atrial septal defect , P＝0.001 ;Pearson correlation analysis indicated that postoperative heart rate change was not correlated with age ,occluder size and pulmonary artery systolic pressure (PASP ) ( r＝0.017－0.182 , P＞0.05 all) . Compared with patients without preoperative pulmonary artery hypertension ,there was sig‐nificant rise in postoperative reduction amplitude of heart rate [ (2.28 ± 9.81) beats／min vs. (11. 35 ± 10.73) beats／min] in those with preoperative elevated pulmonary systolic pressure (≥25mmHg) , P＝0.038 .Conclusion : After percutaneous interventional closure ,heart rate significantly decreases in patients with atrial septal defect .Presence of preoperative pulmonary artery hypertension can be regarded as a risk predictor for postoperative heart rate reduction .
ABSTRACT
Objective To study the changes of sex hormone levels and the intervention of Chinese medicine female depression patients of kidney deficiency and liver depression type.Methods According to CCMD-3 and ICD-10 depressive episodes diagnostic criteria and the Chinese medicine dialectical criteria,120 patients from March 2007 to March 2011 were selccted and randomly recruited into a treatment group (n=60) and a control group (n=60),respectively.The treatment group was treated with traditional Chinese medicine with the functions of tonifying kidney and soothing liver,while the control group was treated with paroxetine.Both groups were treated for 12 weeks.Another healthy group of 60 cases was also setup.HAMD score and symptom score were used to observe the curative effects,the changes of E2,P,and PRL were observed in the patients and healthy persons.Results In the treatment group:E2 levels increased,PRL decreased,compared with the same group before treatment,the difference was statistically significant,[before treatment,E2=(103.6±28.24)pmol/L,after treatment,E2=(167.7± 30.46)pmol/L,P＜0.01; before treatment,PRL=(32.5 ±7.61)μg/L,after treatment,PRL=(15.3±5.92)μg/L,P＜0.01],Compared with the healthy group,the difference was not statistically significant,[healthy group E2=(176.3±33.63) pmol/L,PRL=(12.7±5.23) μg/L,P＞0.05) ].Although the E2 level of the control group after treatment was significantly elevated than the same group before the treatment [before treatment E2=(101.3±27.18)pmol/L,after treatment E2=(142.1 ±30.11)pmol/L,P＜0.01 ],but compared with healthy controls,the differences were statistically significant [healthy group E2=(176.3±33.63)pmol/L,P＜0.01].Conclusion The method of tonifying kidney and soothing liver has effective interventions on sex hormone secretion in depression patients and improvement in patients with depressive mood.
ABSTRACT
Objective To explore the feasibility of right ventricular outflow tract index in the evaluation on right ventricular systolic function and its relationship to other right ventricular functional indices generally accepted in clinical practice. Methods Sixty-one patients with heart failure were randomly selected and divided into elevated right side pressure group and normal right side pressure group by pressure gradient ≥35 mm Hg aquired from tricuspid regurgitation velocity. Twenty-four healthy adults were selected as control group. All the people experienced transthoracic echocardiography. Right ventricular longitudinal excursion(RVLX), right ventricular ejection fraction(RVEF), right ventricular outflow-tract fractional shortening(RVOTFS) and right ventricular ejection time(RVET) were measured, and their differences were compared between healthy adults and heart failure patients as well as between elevated right side pressure group and normal right side pressure group. Relationships of RVOTFS with other right ventricular functional indices were also analyzed. Results Compared with healthy adults, heart failure patients had lower RVOTFS((0.49)?(0.13) vs (0.22)?(0.09),P